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Segal Trials

When Nothing Works: What to Know About Treatment-Resistant Depression

What Is Treatment-Resistant Depression?

For many people, depression is a condition that eventually improves with the right combination of therapy, support, and medication. But for others, the road is more difficult. If you’ve tried multiple antidepressants with little or no relief, you may be living with treatment-resistant depression (TRD).

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What Comes After Detox? Facing the Next Step in Opioid Recovery

Detox Isn’t the Finish Line — It’s the Starting Point

Completing a short-term detox is a major milestone. It takes strength, patience, and endurance. But for many people who use opioids, the real challenge begins after withdrawal ends.

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Living Through the Highs: Recognizing Signs of Bipolar Mania

What Does a Manic Episode Really Feel Like?

For some people living with bipolar I disorder, there are moments when life feels sped up — thoughts racing, energy soaring, and sleep barely needed. It might feel powerful at first, but it can quickly spiral into impulsive decisions, conflict, or confusion.

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The Critical Role of Women's Health Studies in Advancing Personalized Medicine

In the field of medical research, the study of women's health is essential, illuminating unique health needs and leading the way in personalized medicine. Historically, much of medical research has focused on male subjects, leaving gaps in our understanding of female-specific health issues. As we advance in healthcare, the focused study of women’s health and sex differences not only improves our understanding but also drives innovations that promise better health outcomes for everyone. This article explores the significant impact of female-centric clinical studies and highlights the efforts of institutions like Segal Trials to address these critical areas.

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Segal Trials are leaders in Psychedelics Research

The Psychedelic Renaissance: A Leap Forward in Mental Health Treatment

In the wake of the COVID-19 pandemic, humanity has been ushered into what many might call a "new normal," a period marked by profound shifts in our way of life and, notably, in our collective mental health. The psychological aftermath of the pandemic, compounded by other life-altering events, has spotlighted an undeniable crisis: a dramatic surge in mental health issues, burdening an already overwhelmed and antiquated mental health treatment system. Traditional treatments for conditions like addiction, anxiety, depression, and PTSD have remained largely unchanged for decades, sparking a crucial conversation about the need for innovation in mental health care.

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Segal Trials Psychedelics clinical trials now

Psychedelics: a game-changer in mental health?

The resurgence of interest in psychedelics, once sidelined by regulatory crackdowns and societal skepticism, marks a pivotal turn in the quest for effective mental health treatments. Psychedelic drugs, encompassing substances like psilocybin (found in magic mushrooms), LSD, MDMA (ecstasy), and ayahuasca, have moved from the fringes of scientific inquiry to the forefront of innovative psychiatric research. This article delves into how psychedelics are revolutionizing the treatment of mental illnesses such as anxiety, depression, addiction, and PTSD, the limitations of current pharmaceutical options, and the promising horizon of psychedelic-assisted therapy, underscored by rigorous clinical research aiming for FDA approval.

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A Thanksgiving Tribute to Our Segal Trials Champions

As we gather to celebrate Thanksgiving, it's time to shine a spotlight on the unsung heroes of the Segal Trials. In this special tribute, we applaud the selfless volunteers who harmonize science and solidarity, transforming clinical studies into a symphony of hope and progress. Join us in honoring their invaluable contribution.

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