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Segal Trials

ADHD and Anxiety: When Focus is a Fight and Worry Won’t Let Go

What if managing ADHD and anxiety didn’t mean juggling multiple daily pills or powering through therapies that never seem to fully connect? A growing number of researchers are asking the same question—and exploring new options that could better address the unique challenges of living with both conditions. For those who face constant distraction paired with relentless worry, this dual diagnosis can feel like a never-ending loop. But understanding the overlap may be the key to unlocking better care.

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Rethinking Depression: What If You've Already Tried Everything?

For millions living with Treatment-Resistant Depression (TRD), the usual approaches, therapy, antidepressants, or both, just aren’t enough. TRD is more than just “feeling down.” It’s a relentless condition where symptoms persist despite multiple treatment attempts, leaving people stuck in cycles of medication changes, side effects, and frustration.

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Exploring New Paths for Schizophrenia Care

Living with schizophrenia isn’t just about managing symptoms, it’s about navigating a reality that can feel unpredictable and isolating. Whether you're personally affected or supporting someone who is, understanding this condition is the first step toward finding stability and hope. From sudden psychotic episodes to long-term challenges with thinking and motivation, schizophrenia affects every part of life, but new research is bringing fresh insights and potential breakthroughs.

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Exploring a New Path for Anxiety Relief: Inside Psychedelic Research

What if anxiety care didn’t mean taking a pill every day or endlessly pushing through talk therapy that doesn’t quite stick? A growing number of researchers are asking that same question—and turning their attention to a new possibility: psychedelic-assisted therapy. Currently under investigation in advanced clinical trials, this approach combines guided psychedelic sessions with therapeutic support to explore how it may impact people living with chronic anxiety.

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What Happens When Antidepressants Aren’t Enough?

For many, depression is an invisible battle — a daily weight that colors every thought, decision, and moment. While some find relief through therapy or antidepressants, others continue to struggle despite trying multiple medications. This is known as treatment-resistant depression (TRD), and it affects a significant number of people diagnosed with Major Depressive Disorder (MDD).

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Exploring Psychedelic Research for Generalized Anxiety Disorder

Anxiety isn’t always fleeting. For millions of adults, it’s a daily, debilitating experience.
Generalized Anxiety Disorder (GAD) affects approximately 3.1% of U.S. adults each year, and many find limited relief even after trying traditional medications like SSRIs or benzodiazepines[^1]. Symptoms often include excessive worry, restlessness, sleep disturbances, and difficulty concentrating — lasting six months or more and affecting relationships, work, and daily life.

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