Segal Trials

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Depression

Postpartum depression clinical study

Exploring New Frontiers in Postpartum Depression Treatment: A Look at Psychedelics and Ongoing Clinical Studies

Postpartum depression (PPD) continues to be a significant challenge affecting many new mothers, altering the joyous occasion of childbirth into a time of struggle and emotional turmoil. With advances in medical research, new treatment avenues are opening up, offering hope where traditional methods might fall short. One such promising field is the use of psychedelics in treating mood disorders like PPD.

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Psychedelics: a game-changer in mental health?

The resurgence of interest in psychedelics, once sidelined by regulatory crackdowns and societal skepticism, marks a pivotal turn in the quest for effective mental health treatments. Psychedelic drugs, encompassing substances like psilocybin (found in magic mushrooms), LSD, MDMA (ecstasy), and ayahuasca, have moved from the fringes of scientific inquiry to the forefront of innovative psychiatric research. This article delves into how psychedelics are revolutionizing the treatment of mental illnesses such as anxiety, depression, addiction, and PTSD, the limitations of current pharmaceutical options, and the promising horizon of psychedelic-assisted therapy, underscored by rigorous clinical research aiming for FDA approval.

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Understanding Postpartum Depression

Postpartum depression (PPD) is a complex mood disorder that affects many new mothers in the weeks and months following childbirth. It’s essential to understand that PPD is more than just "baby blues," a term used to describe the mild, short-term sadness many women feel after giving birth. The symptoms of PPD can range from persistent feelings of sadness, hopelessness, and worthlessness to overwhelming fatigue, severe anxiety, and even thoughts of harming oneself or the baby. Some of the contributing factors include hormonal changes after childbirth, a history of depression or anxiety, childbirth-related trauma, and various stressors associated with new motherhood.

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Missed the Psychedelics Webinar, Catch it here.

In recent years, the exploration of psychedelics' therapeutic potential has sparked a remarkable revolution in mental health research. With prejudice giving way to evidence-based understanding, scientists are delving deeper into the profound impact psychedelics may have on mental well-being. This blog post examines the significance of psychedelics research in transforming mental health treatment, offering a glimmer of hope to millions worldwide.

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Understanding the Role of Placebos in Clinical Trials

Clinical trials are crucial for the development and evaluation of new medical treatments and interventions. A key component of these trials is the use of placebos, which play a critical role in understanding the efficacy and safety of investigational drugs or treatments. In this article, we will research the concept of placebos in clinical trials, explore examples of placebos, discuss the pros and cons of placebo-controlled trials, examine the role of placebos in drug studies, and address the ethical issues associated with their use.

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Clinical Research Studies for Depression

We Chose a Clinical Trial for Depression and Here's Why

Major depressive disorder (MDD) or Depression is often described as having a loss of interest in daily activities and feeling hopeless. As discussed in our previous blog with Dr. Kakar, A Board Certified Psychiatrist Shares Surprising Facts About Depression, while those are common symptoms, depression varies by every individual. Depression varies by treatments, triggers, and the impact of MDD on a person’s life. In this blog, we’re unpacking those differences and sharing patients’ insights on clinical trials. 

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