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For many people living with depression, treatment brings relief over time. But for others, the symptoms remain — heavy, persistent, and disruptive — even after trying medications, therapy, or both.
For many people, depression is a condition that eventually improves with the right combination of therapy, support, and medication. But for others, the road is more difficult. If you’ve tried multiple antidepressants with little or no relief, you may be living with treatment-resistant depression (TRD).