Explore Our Blog: Expert Articles and Updates​

Posts by:

Segal Trials

How Safe Are Psychedelic Studies for Depression? Understanding the Science and Safeguards

Over the past few years, psychedelics have captured growing attention in mental health research. From psilocybin (the active compound in “magic mushrooms”) to LSD and DMT, these substances are being studied in clinical settings to better understand their potential to relieve symptoms of depression, especially in cases where traditional treatments have not worked.

Read More

Small Daily Steps: How Consistency Helps Stabilize Bipolar Depression

Understanding Bipolar Depression

Bipolar disorder is often described as a condition of highs and lows, alternating periods of mania or hypomania and depression. But what many don’t realize is that bipolar depression can be the most persistent and challenging phase to manage. Feelings of hopelessness, fatigue, and loss of motivation can interfere with daily life and make it difficult to maintain stability.

Read More

What to Expect When Joining a Clinical Trial

Clinical trials are often described as the bridge between medical discovery and real-world care. Every medication, therapy, or medical device we use today went through clinical research before becoming available. Yet for many people, the idea of participating in a clinical trial can feel confusing or even intimidating.

That’s why we’ve created this guide, to walk you through what the process looks like, step by step, and to show you that you’re never alone. Clinical trials are carefully designed to prioritize your safety, respect your time, and give you a chance to make a meaningful contribution to the future of medicine.

Read More

Psilocybin: A New Care Option for Depression When Traditional Treatments Fall Short

For many people living with major depressive disorder (MDD), the journey to relief can be long and frustrating. Standard treatments, such as antidepressants and psychotherapy, are often the first line of care. But for some, these approaches bring only partial improvement or no improvement at all.

Read More

Why ADHD and Anxiety So Often Go Hand in Hand

If you live with Attention-Deficit/Hyperactivity Disorder (ADHD), you might notice that feeling anxious isn’t unusual. In fact, anxiety is one of the most common conditions to occur alongside ADHD, and it’s more than just a coincidence. Mental health experts have long observed a strong connection between the two, especially in adults.

Read More

What Living with Bipolar Depression Really Feels Like

Bipolar disorder is often portrayed in movies and media as extreme energy bursts, impulsive decisions, or erratic behavior. What you rarely see is the crushing depression that follows. For people living with bipolar I or II disorder, depressive episodes are not just bad days. They are consuming periods of sadness, exhaustion, and hopelessness that can last for weeks or even months.

Read More

Behind the Curtain: What Living with Opioid Use Disorder Really Feels Like

Opioid Use Disorder (OUD) is one of the most complex and misunderstood health challenges facing millions today. It is not simply a matter of addiction or choice. It is a chronic, relapsing condition that affects the brain, the body, and nearly every part of daily life. For those living with OUD, the struggle is often invisible to others but deeply felt in every moment.

Read More

Could Psychedelics Be the Future of Anxiety Care? A Look at Promising GAD Clinical Studies

Generalized Anxiety Disorder (GAD) affects millions of adults, often leading to persistent worry, restlessness, and difficulty concentrating. While current treatments—like SSRIs and talk therapy—can help, they don’t work for everyone. New research suggests that psychedelics may offer a novel path forward for those with treatment-resistant anxiety.

Read More