Exploring Psychedelic Research for Generalized Anxiety Disorder

Anxiety isn’t always fleeting. For millions of adults, it’s a daily, debilitating experience.
Generalized Anxiety Disorder (GAD) affects approximately 3.1% of U.S. adults each year, and many find limited relief even after trying traditional medications like SSRIs or benzodiazepines[^1]. Symptoms often include excessive worry, restlessness, sleep disturbances, and difficulty concentrating — lasting six months or more and affecting relationships, work, and daily life.

For individuals who have tried medications with limited success, new research is exploring alternative care options — including psychedelic-assisted therapy.


Why Psychedelics for Anxiety?

Recent clinical interest in psychedelics stems from their unique mechanism of action. Unlike traditional anti-anxiety medications that require daily use, psychedelic compounds are being investigated for their potential to create rapid, lasting effects after just one or two doses, when combined with therapeutic support[^2].

The current study is evaluating how a novel psychedelic compound, administered intramuscularly, may affect:

  • Anxiety symptoms measured by the Hamilton Anxiety Rating Scale (HAM-A)

  • Quality of life, sleep quality, and daily functioning

  • Participant safety and tolerability

Participants also receive therapeutic support sessions before and after dosing to help prepare for and integrate the experience.


Who Qualifies?

This study is designed for adults aged 18 to 65 who:

  • Have been diagnosed with moderate to severe Generalized Anxiety Disorder

  • Have tried medication (antidepressants or anxiolytics) but still experience significant anxiety

  • Are not currently taking benzodiazepines or other serotonin agonists


Psychedelic Research: A Growing Field

Research into psychedelic therapy is progressing rapidly. Studies from leading institutions such as Johns Hopkins and Imperial College London have shown promising effects on anxiety and depression symptoms, particularly when treatment is paired with psychological support[^3][^4].

To learn more about GAD and treatment-resistant anxiety:


Explore a New Care Option

If you or someone you know is living with persistent anxiety and seeking new options beyond conventional medications, clinical research may offer a different path. Participation in studies like this one helps advance science and may open doors to novel approaches in care.

Check if you qualify for a paid clinical study click here! 

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